Depo-Medrol is used as a replacement of glucocorticoid activity in patients with adrenal insufficiency, as an anti-inflammatory agent, and as an immunosuppressive agent.

You need to add a PET to your profile before...
Add One Now

You need to add a VET to your profile before...
Add One Now


Depo-Medrol Basics
Depo-Medrol is available by prescription only. Depo-Medrol is an injectable steroid with similar properties to prednisone and dexamethasone. The active ingredient in Depo-Medrol is methylprednisolone acetate. Methylprednisolone is an anti-inflammatory steroid. Depo-Medrol is used to treat many conditions, including musculoskeletal conditions, allergies, and severe infections with toxicity. Intrasynovial injection of Depo-Medrol can be administered to horses and dogs. Intramuscular injection of Depo-Medrol can be administered to cats, dogs, and horses.

Depo-Medrol Warnings
Keep out of the reach of children and pets. Chronic use of steroids or high doses of steroids can result in hyperadrenocorticism. Depo-Medrol may mask symptoms of serious infections. Monitor your pet and speak to your veterinarian if you notice unusual behavior. Depo-Medrol is not for human use. Do not use Depo-Medrol if your pet is pregnant or nursing. Use Depo-Medrol cautiously if your pet suffers from chronic heart failure, Cushing’s syndrome, diabetes mellitus, hypertension, or osteoporosis. Tell your veterinarian about any pre-existing conditions your pet may have. Do not give Depo-Medrol with NSAIDs. Depo-Medrol should not be given along with Rimadyl or other NSAIDs as there is an increased risk of GI ulcers. Use of corticosteroids with an active infection without the concurrent use of antibiotics could result in a severe infection. Store Depo-Medrol at room temperature.

Depo-Medrol Directions
Give as directed by your veterinarian. Follow the instructions printed on the prescription label. Store Depo-Medrol at room temperature. Complete the prescription to ensure a full recovery, even if your pet seems to be improving, unless instructed otherwise by your veterinarian. Store Depo-Medrol at room temperature.

If you notice any behavioral or physiological changes in your pet during Depo-Medrol treatment, contact your veterinarian immediately.

Additional information

Prescription Strength

20mg/1mL, 20mL Vial, 40mg/1mL, 5mL Vial