Fludrocortisone is used to treat Addison’s disease in dogs and cats.

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Fludrocortisone Basics
Fludrocortisone is available by prescription only. Fludrocortisone is an extra-label drug used when the adrenal gland has lost the ability to produce cortisol and aldosterone. Fludrocortisone is used to treat hypoadrenocorticism, or Addison’s disease. Hypoadrenocorticism is an autoimmune disease that destroys the outer layers of the adrenal gland. These layers are responsible for producing vital hormones, including cortisol and aldosterone. Fludrocortisone replaces aldosterone to help the kidneys balance the concentration of sodium and potassium in your pet’s body.

Fludrocortisone Warnings
Keep out of the reach of children and pets. Do not use in dogs with known fludrocortisone allergies. Blood tests must be done regularly to monitor the effects of fludrocortisone treatment. Fludrocortisone may interact with some other medications. Inform your veterinarian of any and all medications your pet is taking, especially furosemide, digoxin, warfarin, insulin, phenytoin, or aspirin. Store at room temperature. Store protected from light and moisture.

Fludrocortisone Directions 
Give as directed by your veterinarian. Follow the instructions printed on the prescription label. Store at room temperature. Complete the prescription to ensure a full recovery, even if your pet seems to be improving, unless instructed otherwise by your veterinarian. Give with food. Do not stop giving fludrocortisone suddenly.

Dosage FAQs
In the case of a missed dose of fludrocortisone, give it as soon as you remember or wait until it is time to give the next dose. DO NOT GIVE A DOUBLE DOSE OF FLUDROCORTISONE. In the case of an overdose of fludrocortisone, seek immediate attention from your veterinarian. The following symptoms could be signs of an overdose Cushing’s disease, low potassium levels, high blood pressure, weight gain, or swelling or water retention.

If you notice any behavioral or physiological changes in your pet while administering fludrocortisone, contact your veterinarian immediately.

Adverse Reactions and Serious Side Effects
Adverse reactions and serious side effects are rare, but in the case of an adverse reaction or a serious side effect, seek veterinary attention. Some common signs of allergic reactions and serious side effects are facial swelling, breathing difficulties, increased blood pressure, sudden weight gain, glaucoma, thinning of the skin, cataracts, or behavioral changes.

Additional information



Prescription Strength