Heartgard Plus for Dogs



Buy 6 or More Months, Get 15% Off

Buy 12 Months, Get 20% Off


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Heartgard Plus is a monthly heartworm prevention that protects against hookworms and roundworms.

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Heartgard Plus Basics

Heartgard Plus is a monthly preventative that treats heartworms, microfilaria, hookworms, and roundworms. It is used to kill or prevent parasitic diseases. The active ingredients in this medication are ivermectin and pyrantel pamoate. Together, these ingredients control a wide spectrum of parasites by causing neurological damage to the parasites.

Heartgard Plus requires a prescription from your veterinarian. It comes in highly palatable, beef-flavored chewable tablets.

Heartgard Plus Directions

Give as directed by your veterinarian, and always follow the instructions printed on the prescription label. Administer this medication by mouth once every 30 days. Dosage is based on your pet’s weight. Store at room temperature, protected from light and moisture.

Heartgard Plus Dosage

  • 0-25 lbs (blue box): Give one tablet by mouth once monthly.
  • 26-50 lbs (green box): Give one tablet by mouth once monthly.
  • 51-100 lbs (brown box): Give one tablet by mouth once monthly.
  • Over 100 lbs: Give a combination of 2 chewable tablets by mouth once monthly according to your dog’s weight.

Heartgard Plus Warnings

Keep out of the reach of children and pets. Do not use in puppies that are less than 6 weeks old. Do not administer to dogs with known allergies to Heartgard Plus or any of its ingredients. Use caution when administering this medication to collies or collie mixed breeds due to potential toxic effects. Periodic tests for heartworms should be done by your veterinarian before giving your dog this medication. This medication is not effective against tapeworms. In the case of a missed dose, give it as soon as you remember or wait until it is time to give the next dose. Do not give a double dose of this mediation. If you notice any behavioral or physiological changes in your pet during treatment, contact your veterinarian immediately.

If you have any additional questions regarding this product, please contact us at (877)220-6337. A member of our pharmacy staff will be happy to assist you!

Additional information


Large Dog 51-100lbs (Sold in Single Months), Medium 26-50lbs (Sold in Single Months), Small 0-25lbs (Sold in Single Months)

Any refills you have will remain on file, however if you don’t see them in your online account, don't worry!
During checkout, select the option that lets us know your refill is on file.