Lutalyse is a naturally occurring protsaglandin that is used for estrus synchronization in cattle, swine, and mares.

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Lutalyse Basics
Lutalyse is available by prescription only. Lutalyse contains prostaglandin F2 alpha. Prostaglandins are heavily involved in stimulating birth and ovulation. Lutalyse is used to stimulate estrus synchronization, treat infection of the uterus, or pyometra, stimulate abortion in beef cows and heifers, and stimulate breeding in mares. While using lutalyse will help with reproduction in cattle, cattle breeding programs must be properly managed to see results.

Lutalyse Warnings
Keep out of reach of children and pets. This product is not intended for human use. Lutalyse is absorbed through the skin, and should be handled with caution, especially by pregnant women or people suffering from asthma or respiratory problems. If lutalyse touches your skin, wash it off immediately. Lutalyse is not intended for intravenous injection. Use in pregnant animals can induce abortion or parturition. Store at room temperature. Do not let lutalyse freeze. Use product within 12 days of opening.

Lutalyse Directions:
Use as directed by your veterinarian. Follow the instructions printed on the prescription label. Do not puncture stopper greater than 20 times. Protect from freezing. Lutalyse should be given by intramuscular injection only. Disinfect the stopper of the vial before use. Do not enter the vial stopper more than 20 times. 100 mL bottles should be used for cattle only to avoid damage to the vial stopper. Do not administer to sows/gilts prior to 3 days of normal farrowing. In mares, lutalyse is ineffective when administered prior to day 5 after ovulation.

Lutalyse Dosage Instructions:

  • Cattle: 25mg (5ml) per cattle administered by IM injection
  • Swine: 10mg (2ml) per pig administered by IM injection
  • Mares: 1mg per 100lb (45.5kg) body weight

If you notice any unusual behavioral or physiological changes in your pet while giving lutalyse, contact your veterinarian immediately.

Serious Side Effects
Serious injection site infections can occur. Contact your veterinarian immediately if you believe an infection at the injection site has occurred. Side effects in mares were typically seen within 15min of injection and disappeared within one hour.

Additional information

Package Size

30 mL (5 mg/mL), 100 mL (5 mg/mL)