Tri-Heart Plus


Tri-Heart® Plus is an easy-to-administer chewable that helps keep your dog free of heartworm and other dangerous parasites.

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Tri-Heart Plus Basics

Tri-Heart Plus is a heartworm preventative. This medication prevents infestation by heartworms, roundworms, and hookworms. It contains two active ingredients, ivermectin and pyrantel pamoate. Together, these ingredients cause neurological damage to parasites. This leads to the paralysis and death of heartworms, roundworms, and hookworms.

Tri-Heart Plus requires a prescription from your veterinarian. It is available in three strengths depending on your pet’s weight range.

Tri-Heart Plus Directions

Use as directed by your veterinarian, and follow all instructions printed on the prescription label. Administer tablets by mouth once monthly, and be sure to administer year round. Dosage is based on your pet’s weight.

Store at room temperature, protected from light and moisture.

Tri-Heart Plus Dosage

  • 0 – 25 lbs (Blue Box): Give 1 tablet by mouth every 30 days.
  • 26 – 50 lbs (Green Box): Give 1 tablet by mouth every 30 days.
  • 51 – 100 lbs (Brown Box): Give 1 tablet by mouth every 30 days.
  • Over 100 lbs: Use a combination of weight ranges that equal your pet’s weight.

Tri-Heart Plus Warnings

Keep out of the reach of children and pets. Tri-Heart Plus is not intended for human consumption. It is for use in dogs only. Do not use in dogs less than 6 weeks of age. In addition, do not use in dogs with a known allergy or hypersensitivity to ivermectin.  Do not use this medication in dogs with existing heartworm infections. Doing so can lead to serious side effects. Therefore, it is important to have your pet tested for an existing heartworm infection prior to starting this medication. This product may interact with some other medications. Be sure to inform your veterinarian of any and all medications your pet may be taking. Finally, if you notice any behavioral or physiological changes in your pet while giving Tri-Heart Plus, contact your veterinarian immediately.

If you have any additional questions regarding this product, please contact us at (877)220-6337. A member of our pharmacy staff will be happy to assist you!

Additional information

Weight Range

1-25 lbs, 26-50 lbs, 51-100 lbs

Package Size

6 Month Box